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Pharmacokinetics of Posaconazole Coadministered with Antacid in Fasting or Nonfasting Healthy Men

Posaconazole is a potent broad-spectrum azole antifungal agent in clinical development for the treatment of invasive fungal infections. This study evaluated the potential for a pH-dependent pharmacokinetic interaction between posaconazole and an antacid (Mylanta), under fasting and nonfasting condit...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Courtney, Rachel, Radwanski, Elaine, Lim, Josephine, Laughlin, Mark
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982768/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.804-808.2004
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