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Astrocytic expression of HIV-1 Nef impairs spatial and recognition memory

Despite the widespread use of antiretroviral therapy that effectively limits viral replication, memory impairment remains a dilemma for HIV infected people. In the CNS, HIV infection of astrocytes leads to the production of the HIV-1 Nef protein without viral replication. Post mortem studies have fo...

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Detalhes bibliográficos
Main Authors: Chompre, Gladys, Cruz, Emmanuel, Maldonado, Lucianette, Rivera-Amill, Vanessa, Porter, James T., Noel, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530662/
https://ncbi.nlm.nih.gov/pubmed/22926191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.08.007
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