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Nicotinic Acetylcholine Receptor Mediates Nicotine-Induced Actin Cytoskeletal Remodeling and Extracellular Matrix Degradation by Vascular Smooth Muscle Cells

Cigarette smoking is a significant risk factor for atherosclerosis, which involves the invasion of vascular smooth muscle cells (VSMCs) from the media to intima. A hallmark of many invasive cells is actin cytoskeletal remodeling in the form of podosomes, accompanied by extracellular matrix (ECM) deg...

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Detalhes bibliográficos
Main Authors: Gu, Zhizhan, Fonseca, Vera, Hai, Chi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530635/
https://ncbi.nlm.nih.gov/pubmed/22940282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2012.08.003
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