Powerful Identification of Cis-regulatory SNPs in Human Primary Monocytes Using Allele-Specific Gene Expression

A large number of genome-wide association studies have been performed during the past five years to identify associations between SNPs and human complex diseases and traits. The assignment of a functional role for the identified disease-associated SNP is not straight-forward. Genome-wide expression...

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Main Authors: Almlöf, Jonas Carlsson, Lundmark, Per, Lundmark, Anders, Ge, Bing, Maouche, Seraya, Göring, Harald H. H., Liljedahl, Ulrika, Enström, Camilla, Brocheton, Jessy, Proust, Carole, Godefroy, Tiphaine, Sambrook, Jennifer G., Jolley, Jennifer, Crisp-Hihn, Abigail, Foad, Nicola, Lloyd-Jones, Heather, Stephens, Jonathan, Gwilliam, Rhian, Rice, Catherine M., Hengstenberg, Christian, Samani, Nilesh J., Erdmann, Jeanette, Schunkert, Heribert, Pastinen, Tomi, Deloukas, Panos, Goodall, Alison H., Ouwehand, Willem H., Cambien, François, Syvänen, Ann-Christine
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530574/
https://ncbi.nlm.nih.gov/pubmed/23300628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052260
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