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Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals Trans-Regulated Gene Modules in Humans

One major expectation from the transcriptome in humans is to characterize the biological basis of associations identified by genome-wide association studies. So far, few cis expression quantitative trait loci (eQTLs) have been reliably related to disease susceptibility. Trans-regulating mechanisms m...

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Bibliografiska uppgifter
Huvudupphovsmän: Rotival, Maxime, Zeller, Tanja, Wild, Philipp S., Maouche, Seraya, Szymczak, Silke, Schillert, Arne, Castagné, Raphaele, Deiseroth, Arne, Proust, Carole, Brocheton, Jessy, Godefroy, Tiphaine, Perret, Claire, Germain, Marine, Eleftheriadis, Medea, Sinning, Christoph R., Schnabel, Renate B., Lubos, Edith, Lackner, Karl J., Rossmann, Heidi, Münzel, Thomas, Rendon, Augusto, Consortium, Cardiogenics, Erdmann, Jeanette, Deloukas, Panos, Hengstenberg, Christian, Diemert, Patrick, Montalescot, Gilles, Ouwehand, Willem H., Samani, Nilesh J., Schunkert, Heribert, Tregouet, David-Alexandre, Ziegler, Andreas, Goodall, Alison H., Cambien, François, Tiret, Laurence, Blankenberg, Stefan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228821/
https://ncbi.nlm.nih.gov/pubmed/22144904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002367
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