The RenTg Mice: A Powerful Tool to Study Renin-Dependent Chronic Kidney Disease

BACKGROUND: Several studies have shown that activation of the renin-angiotensin system may lead to hypertension, a major risk factor for the development of chronic kidney disease (CKD). The existing hypertension-induced CDK mouse models are quite fast and consequently away from the human pathology....

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Bibliographic Details
Main Authors: Huby, Anne-Cecile, Kavvadas, Panagiotis, Alfieri, Carlo, Abed, Ahmed, Toubas, Julie, Rastaldi, Maria-Pia, Dussaule, Jean-Claude, Chatziantoniou, Christos, Chadjichristos, Christos E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530557/
https://ncbi.nlm.nih.gov/pubmed/23300650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052362
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