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Restoration of Podocyte Structure and Improvement of Chronic Renal Disease in Transgenic Mice Overexpressing Renin

BACKGROUND: Proteinuria is a major marker of the decline of renal function and an important risk factor of coronary heart disease. Elevated proteinuria is associated to the disruption of slit-diaphragm and loss of podocyte foot processes, structural alterations that are considered irreversible. The...

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Bibliografski detalji
Glavni autori: Huby, Anne-Cécile, Rastaldi, Maria-Pia, Caron, Kathleen, Smithies, Oliver, Dussaule, Jean-Claude, Chatziantoniou, Christos
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725297/
https://ncbi.nlm.nih.gov/pubmed/19696925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006721
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