The Stress-Response Gene redd1 Regulates Dorsoventral Patterning by Antagonizing Wnt/β-catenin Activity in Zebrafish

REDD1/redd1 is a stress-response gene that is induced under various stressful conditions such as hypoxia, DNA damage, and energy stress. The increased REDD1 inhibits mTOR signaling and cell growth. Here we report an unexpected role of Redd1 in regulating dorsoventral patterning in zebrafish embryos...

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Hlavní autoři: Feng, Qiang, Zou, Xia, Lu, Ling, Li, Yun, Liu, Yunzhang, Zhou, Jianfeng, Duan, Cunming
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530439/
https://ncbi.nlm.nih.gov/pubmed/23300740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052674
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