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Disruption of the X-loop turn of the prion protein linked to scrapie resistance
The prion diseases are a class of neurodegenerative diseases caused by the misfolding and aggregation of the prion protein (PrP(C)) into toxic and infectious oligomers (PrP(Sc)). These oligomers are critical to understanding and combating these diseases. Differences in the sequence of PrP affect dis...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530274/ https://ncbi.nlm.nih.gov/pubmed/22447804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzs009 |
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