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The kappa opioid receptor agonist U-50488 blocks Ca(2+) channels in a voltage-and G protein-independent manner in sensory neurons
BACKGROUND AND OBJECTIVES: Kappa opioid receptor (κ-OR) activation is known to play a role in analgesia and central sedation. The purpose of the present study was to examine the effect of the κ-OR agonist, U-50488 (an arylacetamide), on Ca(2+) channel currents and the signaling proteins involved in...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530143/ https://ncbi.nlm.nih.gov/pubmed/23222359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AAP.0b013e318274a8a1 |
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