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The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism
The Keap1–Nrf2 [Kelch-like ECH-associated protein 1–nuclear factor (erythroid-derived 2)-like 2] pathway plays a central role in the protection of cells against oxidative and xenobiotic stresses. Nrf2 is a potent transcription activator that recognizes a unique DNA sequence known as the antioxidant...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Frontiers Media S.A.
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530133/ https://ncbi.nlm.nih.gov/pubmed/23272301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00200 |
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