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Brain and circulating levels of Aβ1–40 differentially contribute to vasomotor dysfunction in the mouse brain

BACKGROUND AND PURPOSE: Amyloid-β (Aβ), a peptide that accumulates in the brain and circulates in the blood of patients with Alzheimer’s disease (AD), alters the regulation of cerebral blood flow (CBF) and may contribute to the brain dysfunction underlying the dementia. However, the contributions of...

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Main Authors: Park, Laibaik, Zhou, Ping, Koizumi, Kenzo, Jamal, Sleiman EI, Previti, Mary Lou, Van Nostrand, William E., Carlson, George, Iadecola, Costantino
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530010/
https://ncbi.nlm.nih.gov/pubmed/23204056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.112.670976
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