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Juxtamembrane tryptophans of synaptobrevin 2 control the process of membrane fusion
Synaptobrevin 2 (Syb2), Syntaxin (Sx1A), and SNAP-25, generate a force to induce fusion pore formation. The v-SNARE, Syb2, is anchored to the vesicle membrane by a single transmembrane domain. Here we show that 2 tryptophans (W89/W90) located in the juxtamembrane domain of Syb2, which stabilize the...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529983/ https://ncbi.nlm.nih.gov/pubmed/23178715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.11.002 |
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