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Cleavage of Anti-apoptotic Bcl-2 Family Members After TCR Stimulation Contributes to the Decision Between T Cell Activation and Apoptosis
Engagement of the TCR induces activation-induced cell death (AICD) of T cells that have been previously stimulated. However, a portion of these T cells can survive and undergo further activation. The molecular mechanism that decides whether a T cell will live or die after TCR re-engagement is unclea...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529753/ https://ncbi.nlm.nih.gov/pubmed/23203923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201610 |
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