Twice-Daily Application of HIV Microbicides Alters the Vaginal Microbiota

Vaginal HIV microbicides offer great promise in preventing HIV transmission, but failures of phase 3 clinical trials, in which microbicide-treated subjects had an increased risk of HIV transmission, raised concerns about endpoints used to evaluate microbicide safety. A possible explanation for the i...

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Autors principals: Ravel, Jacques, Gajer, Pawel, Fu, Li, Mauck, Christine K., Koenig, Sara S. K., Sakamoto, Joyce, Motsinger-Reif, Alison A., Doncel, Gustavo F., Zeichner, Steven L.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Microbiology 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529542/
https://ncbi.nlm.nih.gov/pubmed/23249810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00370-12
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