Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival

The precise regulation of Ca(2+) dynamics is crucial for proper differentiation and function of osteoclasts. Here we show the involvement of plasma membrane Ca(2+) ATPase (PMCA) isoforms 1 and 4 in osteoclastogenesis. In immature/undifferentiated cells, PMCAs inhibited receptor activator of NF-κB li...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kim, Hyung Joon, Prasad, Vikram, Hyung, Seok-Won, Lee, Zang Hee, Lee, Sang-Won, Bhargava, Aditi, Pearce, David, Lee, Youngkyun, Kim, Hong-Hee
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529522/
https://ncbi.nlm.nih.gov/pubmed/23266958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201204067
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge