Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival

The precise regulation of Ca(2+) dynamics is crucial for proper differentiation and function of osteoclasts. Here we show the involvement of plasma membrane Ca(2+) ATPase (PMCA) isoforms 1 and 4 in osteoclastogenesis. In immature/undifferentiated cells, PMCAs inhibited receptor activator of NF-κB li...

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Detalhes bibliográficos
Main Authors: Kim, Hyung Joon, Prasad, Vikram, Hyung, Seok-Won, Lee, Zang Hee, Lee, Sang-Won, Bhargava, Aditi, Pearce, David, Lee, Youngkyun, Kim, Hong-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529522/
https://ncbi.nlm.nih.gov/pubmed/23266958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201204067
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