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Creation and preliminary characterization of a Tp53 knockout rat
The tumor suppressor TP53 plays a crucial role in cancer biology, and the TP53 gene is the most mutated gene in human cancer. Trp53 knockout mouse models have been widely used in cancer etiology studies and in search for a cure of cancer with some limitations that other model organisms might help ov...
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| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Limited
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529357/ https://ncbi.nlm.nih.gov/pubmed/22917926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009704 |
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