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LoxP-FRT Trap (LOFT): a simple and flexible system for conventional and reversible gene targeting
BACKGROUND: Conditional gene knockout (cKO) mediated by the Cre/LoxP system is indispensable for exploring gene functions in mice. However, a major limitation of this method is that gene KO is not reversible. A number of methods have been developed to overcome this, but each method has its own limit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529186/ https://ncbi.nlm.nih.gov/pubmed/23198860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-10-96 |
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