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IMPACT OF ACE2 DEFICIENCY AND OXIDATIVE STRESS ON CEREBROVASCULAR FUNCTION WITH AGING

BACKGROUND AND PURPOSE: Angiotensin II produces oxidative stress and endothelial dysfunction in cerebral arteries, and angiotensin II type I receptors may play a role in longevity and vascular aging. Angiotensin converting enzyme type 2 (ACE2) converts angiotensin II to angiotensin (1–7) and thus ma...

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Autors principals: Peña Silva, Ricardo A., Chu, Yi, Miller, Jordan D., Mitchell, Ian J., Penninger, Josef M., Faraci, Frank M., Heistad, Donald D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529166/
https://ncbi.nlm.nih.gov/pubmed/23160880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.112.667063
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