Clinical Pharmacokinetics and Safety of High Doses of Ceforanide (BL-S786R) and Cefazolin

The pharmacokinetics and safety of ceforanide and cefazolin were compared in normal subjects after 30-min intravenous infusions of 2-, 3-, and 4-g single doses and 4-g twice-daily doses for 10 days. No significant differences were observed in plasma-renal pharmacokinetic parameters between single an...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Smyth, Robert D., Pfeffer, Morris, Donald, Aaron Glick, Van Harken, R., Hottendorf, Girard H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1979
Soggetti:	Pharmacology and Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352915/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/526003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.5.615
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