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Amikacin resistance associated with a plasmid-borne aminoglycoside phosphotransferase in Escherichia coli.

Enzymatic phosphorylation of amikacin has not been reported previously in gram-negative bacteria. We found that extracts of MP1, a mutant of Escherichia coli JR66/W677 that is resistant to amikacin, were able to phosphorylate this aminoglycoside more rapidly than were extracts of the parental strain...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Perlin, M H, Lerner, S A
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1979
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352912/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/393165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.5.598
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