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His26 Protonation in Cytochrome c Triggers Microsecond β-sheet Formation and Heme Exposure: Implications for Apoptosis

Cytochrome c unfolds locally and reversibly upon heating at pH 3. UV resonance Raman (UVRR) spectra reveal that instead of producing unordered structure, unfolding converts turns and some helical elements to β-sheet. It also disrupts the Met80-heme bond, and was earlier shown to induce peroxidase ac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Balakrishnan, Gurusamy, Hu, Ying, Spiro, Thomas G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529097/
https://ncbi.nlm.nih.gov/pubmed/23094892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307100a
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