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Structural mechanism of Bax inhibition by cytomegalovirus protein vMIA
The human protein Bax sits at a critical regulatory junction of apoptosis, or programmed cell death. Bax exists in equilibrium between cytosolic and mitochondria-associated forms that shifts toward the latter when Bax is activated by proapoptotic proteins. Activated Bax changes conformation, inserts...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529058/ https://ncbi.nlm.nih.gov/pubmed/23213219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217094110 |
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