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Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA
Replication of human cytomegalovirus (CMV) requires the expression of the viral mitochondria–localized inhibitor of apoptosis (vMIA). vMIA inhibits apoptosis by recruiting Bax to mitochondria, resulting in its neutralization. We show that vMIA decreases cell size, reduces actin polymerization, and i...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064390/ https://ncbi.nlm.nih.gov/pubmed/16982800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604069 |
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