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Capturing reaction paths and intermediates in Cre-loxP recombination using single-molecule fluorescence

Site-specific recombination plays key roles in microbe biology and is exploited extensively to manipulate the genomes of higher organisms. Cre is a well studied site-specific recombinase, responsible for establishment and maintenance of the P1 bacteriophage genome in bacteria. During recombination,...

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Detalles Bibliográficos
Main Authors: Pinkney, Justin N. M., Zawadzki, Pawel, Mazuryk, Jaroslaw, Arciszewska, Lidia K., Sherratt, David J., Kapanidis, Achillefs N.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529024/
https://ncbi.nlm.nih.gov/pubmed/23184986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211922109
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