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Structure of the Holliday junction intermediate in Cre-loxP site-specific recombination.
We have determined the X-ray crystal structures of two DNA Holliday junctions (HJs) bound by Cre recombinase. The HJ is a four-way branched structure that occurs as an intermediate in genetic recombination pathways, including site-specific recombination by the lambda-integrase family. Cre recombinas...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170750/ https://ncbi.nlm.nih.gov/pubmed/9670032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.4175 |
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