High Vascular Delivery of EGF, but Low Receptor Binding Rate Is Observed in AsPC-1 Tumors as Compared to Normal Pancreas

PURPOSE: Cellular receptor targeted imaging agents present the potential to target extracellular molecular expression in cancerous lesions; however, the image contrast in vivo does not reflect the magnitude of overexpression expected from in vitro data. Here, the in vivo delivery and binding kinetic...

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Hauptverfasser: Samkoe, Kimberley S., Sexton, Kristian, Tichauer, Kenneth M., Hextrum, Shannon K., Pardesi, Omar, Davis, Scott C., O’Hara, Julia A., Hoopes, P. Jack, Hasan, Tayyaba, Pogue, Brian W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529005/
https://ncbi.nlm.nih.gov/pubmed/21847690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-011-0503-5
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