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Imaging targeted-agent binding in vivo with two probes

An approach to quantitatively image targeted-agent binding rate in vivo is demonstrated with dual-probe injection of both targeted and nontargeted fluorescent dyes. Images of a binding rate constant are created that reveal lower than expected uptake of epidermal growth factor in an orthotopic xenogr...

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Detalhes bibliográficos
Main Authors: Pogue, Brian W., Samkoe, Kimberley S., Hextrum, Shannon, O’Hara, Julia A., Jermyn, Michael, Srinivasan, Subhadra, Hasan, Tayyaba
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909298/
https://ncbi.nlm.nih.gov/pubmed/20614996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3449109
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