Plasma estrone sulfate concentrations and genetic variation at the CYP19A1 locus in postmenopausal women with early breast cancer treated with letrozole

Estrogen synthesis suppression induced by aromatase inhibitors in breast cancer (BC) patients may be affected by single nucleotide polymorphisms (SNPs) of the gene encoding aromatase enzyme, CYP19A1. We assessed the association between plasma estrone sulfate (ES), letrozole treatment, and four SNPs...

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Hauptverfasser: Lunardi, G., Piccioli, P., Bruzzi, P., Notaro, R., Lastraioli, S., Serra, M., Marroni, P., Bighin, C., Mansutti, M., Puglisi, F., Porpiglia, M., Ponzone, R., Bisagni, G., Garrone, O., Cavazzini, G., Clavarezza, M., Del Mastro, L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2012
Schlagworte:
Clinical Trial
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528956/
https://ncbi.nlm.nih.gov/pubmed/23129173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2306-z
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