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HLA-DR and HLA-DP Restricted Epitopes from Human Cytomegalovirus Glycoprotein B Recognized by CD4(+) T-Cell Clones from Chronically Infected Individuals

PURPOSE: Helper CD4(+) T cells presumably play a major role in controlling cytomegalovirus (CMV) by providing help to specific B and CD8(+) cytotoxic T cells, as well as through cytotoxicity-mediated mechanisms. Since CMV glycoprotein B (gB) is a major candidate for a subunit vaccine against CMV, we...

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Bibliografiske detaljer
Main Authors: Ventura, Claire, Bisceglia, Hélène, Girerd-Chambaz, Yves, Burdin, Nicolas, Chaux, Pascal
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528953/
https://ncbi.nlm.nih.gov/pubmed/22797815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-012-9732-x
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