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Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa

BACKGROUND: Recent studies show that activated factor VII (FVIIa) binds to the endothelial cell protein C receptor (EPCR) on the vascular endothelium; however, the importance of this interaction in hemostasis or pathophysiology is unknown. OBJECTIVE: The aim of the present study was to investigate t...

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Hlavní autoři: Clark, C A, Vatsyayan, R, Hedner, U, Esmon, C T, Pendurthi, U R, Rao, L V M
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528836/
https://ncbi.nlm.nih.gov/pubmed/22950420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2012.04917.x
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