Stiffening of Human Mesenchymal Stem Cell Spheroid Microenvironments Induced by Incorporation of Gelatin Microparticles

Culturing multipotent adult mesenchymal stem cells as 3D aggregates augments their differentiation potential and paracrine activity. One caveat of stem cell spheroids, though, can be the limited diffusional transport barriers posed by the inherent 3D structure of the multicellular aggregates. In ord...

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Autori principali: Baraniak, Priya R., Cooke, Marissa T., Saeed, Rabbia, Kinney, Melissa A., Fridley, Krista M., McDevitt, Todd C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528787/
https://ncbi.nlm.nih.gov/pubmed/22658155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2012.02.018
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