MMP-mediated Mesenchymal Morphogenesis of Pluripotent Stem Cell Aggregates Stimulated by Gelatin Methacrylate Microparticle Incorporation

Matrix metalloproteinases (MMPs) remodel the extracellular matrix (ECM) to facilitate epithelialto-mesenchymal transitions (EMTs) and promote cell specification during embryonic development. In this study, we hypothesized that introducing degradable ECM-based biomaterials to pluripotent stem cell (P...

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Veröffentlicht in:Biomaterials
Hauptverfasser: Nguyen, Anh H., Wang, Yun, White, Douglas E., Platt, Manu O., McDevitt, Todd C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907544/
https://ncbi.nlm.nih.gov/pubmed/26519649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.10.043
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