Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues

Aberrant DNA methylation often occurs in colorectal cancer (CRC). In our study we applied a genome-wide DNA methylation analysis approach, MethylCap-seq, to map the differentially methylated regions (DMRs) in 24 tumors and matched normal colon samples. In total, 2687 frequently hypermethylated and 4...

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Bibliografiske detaljer
Main Authors: Simmer, Femke, Brinkman, Arie B., Assenov, Yassen, Matarese, Filomena, Kaan, Anita, Sabatino, Lina, Villanueva, Alberto, Huertas, Dori, Esteller, Manel, Lengauer, Thomas, Bock, Christoph, Colantuoni, Vittorio, Altucci, Lucia, Stunnenberg, Hendrik G.
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528691/
https://ncbi.nlm.nih.gov/pubmed/23079744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22562
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