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Kinetic characterization of the critical step in HIV-1 protease maturation
HIV maturation requires multiple cleavage of long polyprotein chains into functional proteins that include the viral protease itself. Initial cleavage by the protease dimer occurs from within these precursors, and yet only a single protease monomer is embedded in each polyprotein chain. Self-activat...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528573/ https://ncbi.nlm.nih.gov/pubmed/23184967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210983109 |
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