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Cellular crowding imposes global constraints on the chemistry and evolution of proteomes
In living cells, functional protein–protein interactions compete with a much larger number of nonfunctional, or promiscuous, interactions. Several cellular properties contribute to avoiding unwanted protein interactions, including regulation of gene expression, cellular compartmentalization, and hig...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528536/ https://ncbi.nlm.nih.gov/pubmed/23184996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209312109 |
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