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Patterns of evolutionary constraints on genes in humans

BACKGROUND: Different regions in a genome evolve at different rates depending on structural and functional constraints. Some genomic regions are highly conserved during metazoan evolution, while other regions may evolve rapidly, either in all species or in a lineage-specific manner. A strong or even...

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Bibliografiske detaljer
Main Authors: De, Subhajyoti, Lopez-Bigas, Nuria, Teichmann, Sarah A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587479/
https://ncbi.nlm.nih.gov/pubmed/18840274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-275
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