Opsonization of malaria-infected erythrocytes activates the inflammasome and enhances inflammatory cytokine secretion by human macrophages

BACKGROUND: Antibody opsonization of Plasmodium falciparum-infected erythrocytes (IE) plays a crucial role in anti-malarial immunity by promoting clearance of blood-stage infection by monocytes and macrophages. The effects of phagocytosis of opsonized IE on macrophage pro-inflammatory cytokine respo...

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Autors principals: Zhou, Jingling, Ludlow, Louise E, Hasang, Wina, Rogerson, Stephen J, Jaworowski, Anthony
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528456/
https://ncbi.nlm.nih.gov/pubmed/23046548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-343
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