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HIV-1 Inhibits Phagocytosis and Inflammatory Cytokine Responses of Human Monocyte-Derived Macrophages to P. falciparum Infected Erythrocytes

HIV-1 infection increases the risk and severity of malaria by poorly defined mechanisms. We investigated the effect of HIV-1(Ba-L) infection of monocyte-derived macrophages (MDM) on phagocytosis of opsonised P. falciparum infected erythrocytes (IE) and subsequent proinflammatory cytokine secretion....

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Detalhes bibliográficos
Main Authors: Ludlow, Louise E., Zhou, Jingling, Tippett, Emma, Cheng, Wan-Jung, Hasang, Wina, Rogerson, Stephen J., Jaworowski, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283736/
https://ncbi.nlm.nih.gov/pubmed/22363802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032102
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