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SIRT6 is required for maintenance of telomere position effect in human cells

In Saccharomyces cerevisiae, the repressive chromatin environment at telomeres gives rise to telomere position effect (TPE), the epigenetic silencing of telomere-proximal genes. Chromatin-modifying factors that control TPE in yeast have been extensively studied, and among these, the lifespan regulat...

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Autors principals: Tennen, Ruth I., Bua, Dennis J., Wright, Woodring E., Chua, Katrin F.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528101/
https://ncbi.nlm.nih.gov/pubmed/21847107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1443
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