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Telomere Terminal G/C Strand Synthesis: Measuring Telomerase Action and C-rich Fill-in

Telomerase is present in most human cancers, and proliferative stem cells including germline cells. Telomerase plays an essential role in tumorigenesis by maintaining/elongating telomeric DNA, and thus preventing the telomere shortening that results in replicative senescence. Understanding telomeras...

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Main Authors: Zhao, Yong, Shay, Jerry W., Wright, Woodring E.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528099/
https://ncbi.nlm.nih.gov/pubmed/21461812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-092-8_7
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