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Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases

Vascular endothelial growth factors (VEGFs) belong to the platelet-derived growth factor supergene family, and they play central roles in the regulation of angiogenesis and lymphangiogenesis. VEGF-A, the major factor for angiogenesis, binds to two tyrosine kinase (TK) receptors, VEGFR-1 (Flt-1) and...

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Autor principal: Shibuya, Masabumi
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528006/
https://ncbi.nlm.nih.gov/pubmed/23172303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvs136
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