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MK2 Regulates Ras Oncogenesis through Stimulating ROS Production

Ras signals through both mitogenic and stress pathways and studies of Ras regulatory effects of stress pathways hold great promise to control Ras-dependent malignancies. Our previous work showed Ras activation of a stress kinase (MAPK-activated protein kinase 2 [MK2]), and here, we examine regulator...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kobayashi, Yusuke, Qi, Xiaomei, Chen, Guan
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527985/
https://ncbi.nlm.nih.gov/pubmed/23264852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912462718
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