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Multivalent Pseudopeptides Targeting Cell Surface Nucleoproteins Inhibit Cancer Cell Invasion through Tissue Inhibitor of Metalloproteinases 3 (TIMP-3) Release

Blockage of the metastasis process remains a significant clinical challenge, requiring innovative therapeutic approaches. For this purpose, molecules that inhibit matrix metalloproteinases activity or induce the expression of their natural inhibitor, the tissue inhibitor of metalloproteinases (TIMPs...

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Detalhes bibliográficos
Main Authors: Destouches, Damien, Huet, Eric, Sader, Maha, Frechault, Sophie, Carpentier, Gilles, Ayoul, Florie, Briand, Jean-Paul, Menashi, Suzanne, Courty, José
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527954/
https://ncbi.nlm.nih.gov/pubmed/23109338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380402
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