Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice

BACKGROUND: The importance of cell-surface nucleolin in cancer biology was recently highlighted by studies showing that ligands of nucleolin play critical role in tumorigenesis and angiogenesis. By using a specific antagonist that binds the C-terminal tail of nucleolin, the HB-19 pseudopeptide, we r...

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Detalhes bibliográficos
Main Authors: El Khoury, Diala, Destouches, Damien, Lengagne, Renée, Krust, Bernard, Hamma-Kourbali, Yamina, Garcette, Marylène, Niro, Sandra, Kato, Masashi, Briand, Jean-Paul, Courty, José, Hovanessian, Ara G, Prévost-Blondel, Armelle
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912263/
https://ncbi.nlm.nih.gov/pubmed/20573279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-325
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