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Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type

BACKGROUND: Nucleolin expressed at the cell surface is a binding protein for a variety of ligands implicated in tumorigenesis and angiogenesis. By using a specific antagonist that binds the C-terminal RGG domain of nucleolin, the HB-19 pseudopeptide, we recently reported that targeting surface nucle...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Krust, Bernard, El Khoury, Diala, Nondier, Isabelle, Soundaramourty, Calaiselvy, Hovanessian, Ara G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199867/
https://ncbi.nlm.nih.gov/pubmed/21812966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-333
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