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Na(+)/H(+) Exchanger Regulatory Factor 1 (NHERF1) Directly Regulates Osteogenesis
Bone formation requires synthesis, secretion, and mineralization of matrix. Deficiencies in these processes produce bone defects. The absence of the PDZ domain protein Na(+)/H(+) exchange regulatory factor 1 (NHERF1) in mice, or its mutation in humans, causes osteomalacia believed to reflect renal p...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527918/ https://ncbi.nlm.nih.gov/pubmed/23109343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.422766 |
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