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Pathogenesis of hypertrophic cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity

AIMS: The role of calcineurin protein phosphatase 2B (PP2B) in the pathogenesis of human hypertrophic cardiomyopathy (HCM) remains unsettled. We determined potential involvement of calcineurin in the pathogenesis of HCM caused by mutations in myozenin 2 (MYOZ2), an inhibitor of calcineurin. METHODS...

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Bibliografiset tiedot
Päätekijät: Ruggiero, Alessandra, Chen, Suet Nee, Lombardi, Raffaella, Rodriguez, Gabriela, Marian, Ali J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527764/
https://ncbi.nlm.nih.gov/pubmed/22987565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs294
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