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Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms
Alternative splicing is regulated by splicing factors that modulate splice site selection. In some cases, however, splicing factors show antagonistic activities by either activating or repressing splicing. Here, we show that these opposing outcomes are based on their binding location relative to reg...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527730/ https://ncbi.nlm.nih.gov/pubmed/23175589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.037044.112 |
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